Blood type O least vulnerable to Covid; A, AB at most risk

  • Blood type O least vulnerable to Covid; A, AB at most risk

Blood type O least vulnerable to Covid; A, AB at most risk

The study suggests that people with blood types A, B, or AB may be more likely to be infected with Covid-19 than people with type O.

Patients with blood types A and AB also had higher rates of dialysis for kidney failure, suggesting increased organ dysfunction or failure due to COVID-19 (32% vs 95%, P = 0.004). "We have the advantage of a strong control group - Denmark is a small, ethnically homogenous country with a public health system and a central registry for lab data - so our control is population-based, giving our findings a strong foundation".

A preprint study published in March this year suggested that people with blood type A have a higher risk of acquiring Covid-19 compared with non-A blood groups, while another study published in June found that blood type O seemed to be more resistant against Covid-19 infection. This study had said that individuals with O blood type were around 9-18 per cent less likely to test positive for COVID-19 than individuals with other blood types.

Previous studies have indicated similar results in patients with blood type O.

The research papers added evidence that there may be a connection between blood type and susceptibility to COVID-19 but the researchers stated that more studies need to be done to better understand why and what it means for patients. In the first, researchers looked at some 473,654 people in Demark who were tested for COVID-19 between February and July and compared them with the general population of roughly 2.2 million people.

"The Dublin-Boston score is easily calculated and can be applied to all hospitalised Covid-19 patients", said study author Gerry McElvaney from the RCSI University in Ireland.

A separate retrospective study in Canada found that people with blood groups A or AB appear to exhibit greater COVID-19 disease severity than people with blood groups O or B.

Between the blood types A, B and AB, no significant difference in rates of infection was found. Meanwhile, people with blood group O or B, experienced a visit in the ICU with a median of about nine days. After controlling for certain factors, they found fewer patients with blood type O, compared with patients with blood types A, B, and AB.

Interestingly, blood groups, A and AB were also associated with complications post-hospitalization, such as myocarditis, lung injury and renal damage.

Also this summer, the genealogy website 23andMe.com released data they collected from 750,000 participants who identified they have tested positive for COVID-19.