Fringe benefits: drug side effects could treat human hair loss

  • Fringe benefits: drug side effects could treat human hair loss

Fringe benefits: drug side effects could treat human hair loss

The drug has also been linked to a number of side effects such as headaches, vomiting, high blood pressure, and most interestingly, increased hair growth.

Only two drugs approved by the US Food and Drug Administration are now used for hair loss disorders: minoxidil and finasteride.

Scientists believe they may have discovered a cure for baldness with an experimental drug originally created to treat brittle bone disease.

If applied as a shampoo, scientists found the treatment promotes hair growth.

A project by The University of Manchester's Centre for Dermatology Research in England began work by examining an immunosuppressive drug that had always been known to cause hair growth as a side effect.

The article notes that the study was conducted only in a laboratory with samples of hair follicles more than 40 men who have been hair transplant procedure.

The study from the laboratory of Prof Ralf Paus, is published (8 May) in the open access journal PLOS Biology.

However, both these not only have side effects but at the same time do not give satisfying results.

The PhD project, led by Dr Nathan Hawkshaw and colleagues, sought to develop new ways to promote human hair growth with the hope of finding novel, well-tolerated agents for treating androgenetic alopecia.

This medication, Cyclosporine A (CsA), has been commonly used as the 1980s to curb transplant rejection and autoimmune illnesses.

When he then treated hair follicles with WAY-316606, the compound worked like CsA to enhance human hair growth, but without the other side effects.

Hawkshaw said the next phase ought to be a medical test to determine whether WAY-316606, or even similar chemicals, are safe and effective.

Upon analysing the drug, the researchers found CsA reduces the protein SFRP1 in the body, which inhibits the growth of hair follicles.

"That said, more research will need to be done before it can be used by people with hair loss", the spokesman said.

He added: "When the hair growth-promoting effects of CsA were previously studied in mice, a very different molecular mechanism of action was suggested; had we relied on these mouse research concepts, we would have been barking up the wrong tree".